MS-4400 XYZ Automated Stage

About the MS-4400

The MS-4400 XYZ provides a high resolution and highly repeatable means of controlling the X, Y, and Z position of the microscope stage. The MS-4400 XY stage has been specifically designed for larger upright microscopes like the Leica DMR-series, the Nikon Eclipse 80i, the Olympus BX series, and the Zeiss Axioplan, Axioskop 2, and Axio Imager. All axes derive their precise control through the use of closed-loop DC servomotors employing high-resolution rotary encoders for positioning feedback. By using closed-loop control of the stage position, there is no chance that the stage will become lost, as can occur with open-loop micro-stepped stages after a number of moves and direction changes. The MS-4400 XY stage utilizes crossed-roller slides, a high-precision lead screw, and zero-backlash miniature geared DC servomotors for smooth and accurate motion. The Z-axis drive also uses ASI’s proven line of closed-loop motor drives, each custom fitted to the microscope. The microprocessor-controlled MS-2000 control unit provides for RS 232 and USB communication with a host computer.

More Info

MS-4400 Features
  • Closed-loop DC servo control of the X, Y, and Z-axes for precise positioning and highly repeatable focusing
  • Wide dynamic speed range with XY joystick control
  • Utilizes ASI’s proven Z-axis drives
  • Z-axis clutch for easy switching between manual and motor-driven focus control
  • Backlit LCD display shows X, Y, and Z coordinates
  • “Zero” and “Home” button for simple stand-alone operations
  • Compact ergonomic tabletop control unit size is 6″D x 9″W x 3″H
  • Microprocessor control with RS-232 serial and USB communications
  • Proven operation with many popular software packages
MS-4400 Specifications for Standard Configuration
XY axis range of travel 100 mm x 100 mm
XY axis resolution (rotary encoder step) 22 nm
XY axis RMS repeatability < 700 nm
XY axis maximum velocity 7 mm /sec
Z axis resolution (encoder step) 50 nm
Z axis repeatability ± 100 nm
Z axis maximum velocity 0.6 mm/sec
MS-4400 Options
  • X, Y, and Z-axis Linear Encoders for high-accuracy positioning and focus control
  • Stage Inserts to hold a variety of slides, dishes, sealed glass chambers, multiwell microplates, perfusers, heaters, and many other special items
  • Auto-Focus for stages with ASI Z-axis drives (requires NTSC, PAL, or S-Video analog signal)
  • Other lead screw pitches are available
Linear Encoder Options
MS-4400 Linear Encoder Options
Axis Resolution Scale Accuracy
XY 10 nm ± 3 μm per length of scale
Z (12 mm and 15 mm stroke) 50 nm 0.025 μm per mm
Lead Screw Options
MS-4400 Lead Screw Options
Lead Screw Pitch Options Rotary Encoder Resolution Maximum Speed
25.40 mm (Ultra-coarse) 88 nm 28 mm/sec
12.70 mm (Super-coarse) 44 nm 14 mm/sec
6.35 mm (Standard) 22 nm 7 mm/sec
1.59 mm (Fine) 5.5 nm 1.75 mm/sec
0.635 mm (Extra-fine) 2.2 nm 0.7 mm/sec

*Standard Lead Screw Accuracy is 0.25 μm per mm.

Product Compatibility
MS-4400 Product Compatibility
  • Leica – Aristoplan, DM1000, DM2000, DM2500, DM4000, DM4500, DM5000, DM6000, DMRB, DMRP, DMRXP
  • Nikon – Eclipse 80i, Eclipse 90i, Eclipse 800, Eclipse 1000
  • Olympus – AX70, BX41, BX50, BX51, BX60, BX61, BX63
  • Zeiss – AxioImager, Axioplan, Axioplan II, Axiophot I, Axiophot II, Axioskop, Axioskop II, Axioskop FS II